Plasma Homocysteine Levels in Patients with Metabolic Syndrome
نویسندگان
چکیده
Metabolic syndrome is a clinical syndrome in which multiple risks are clustered in an individual and is a common basis of vascular disease in the industrial countries. Metabolic syndrome, dysmetabolic syndrome or insulinresistance syndrome (or syndrome X as it was initially designated), which is closely linked to insulin resistance, is a condition, which is recognized as raising the risk of cardiovascular disease (1,2). It was originally described by Reaven (2) as quartet of hypertension, glucose intolerance and dyslipidemia (high triglyceride, low high-density lipoprotein-cholesterol (HDLcholesterol), with insulin resistance or hyperinsulinemia. Central obesity is often associated and other phenotypes, such as impaired fibrinolysis, microalbuminuria, small dense low-density lipoprotein (LDL) particles and markers of acute phase reactants, were later found to be associated (2-4). The risk of atherosclerosis increased in patients with metabolic syndrome (5). Homocysteine (tHcy) is a sulfur-containing amino acid formed during the metabolism of methionine. PLASMA HOMOCYSTEINE LEVELS IN PATIENTS WITH METABOLIC SYNDROME
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